December 2014
District Council 16 gives $200K for Cancer Research

Money Goes to Effective, Ongoing Research and Treatment.

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November 2014
MesoRFA Newsletter 2014 Winter Edition

Review the activities and events of 2014 at MesoRFA including a report from the lab on Eph-B4 as a Therapy for Mesothelioma.

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October 27, 2014
District Council 16 Aim to Cure 2014

This year's Aim to Cure event saw over 80 participants and generated more than $42,000 for mesothelioma cancer cure research.

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October 2014
Mesothelioma Eph-B4 Treatment Submitted to FDA for Phase I Clinical Trial

A search for novel targets and therapeutics is underway, and recently identified therapeutics includes Eph-B4.

Since the initial study, Eph-B4 has been submitted to the FDA for Phase I Clinical Trials and is currently being offered to patients at the USC/Norris Comprehensive Cancer Center.

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September 23, 2014

John S. Lyons Memorial Banquet of 2014

The Foundation's Assistant Executive Director, Shane Rucker spoke at the event and gave supporters an update on the progress being made by the Mesothelioma Lab at USC Norris Comprehensive Cancer Center.

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July 21, 2014

District Council 16 Golf Invitational of 2014

On July 21st , this year's DC 16 Golf Invitational was truly amazing in the amount of support and dedication to the cause that we have ever seen. With this year's event proceeds topping $90,000...

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June 30, 2014

Roger Hamilton Memorial Golf Invitational - 2014 13th Annual

This year marks the 13th year of the annual event and was held on June 30, 2014 at the pristine Napa Valley Country Club. After a great day on the course, winding through the hills of Napa Valley , golfers joined for dinner and to hear how their donations were being used to help research into this terrible disease. California State Buildings Trades Council President, Robbie Hunter, began by...

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June 6, 2014

California Pipetrades Aim to Cure-Birdslanding, California

The 2014 “ California Pipetrades Aim to Cure” mesothelioma clayshoot, hosted by Foundation Board Member and International Pipetrades Representative, Jim Kellogg, kicked off a great year of fundraising, netting approximately $75,000 for mesothelioma research! On June 6 th , this year's event saw...

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May 16, 2014

Fresno Local 246 Scholarship Golf Tournament

Assistant Executive Director, Shane Rucker, enjoys a day of golf in support of the UA Local 246 Plumbers & Pipefitters Scholarship Golf Tournament.

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Bring your Mesothelioma questions to us: click HERE

DONATIONS for cancer cure

100 percent of all proceeds received are going to the USC Norris Comprehensive Cancer Medical Center in Los Angeles to support the FDA clinical trials. These trials include Veglin, a mesothelioma cancer treatment. Veglin manipulates the blood vessels to starve a malignant tumor while alleviating fluid build up in the lungs

Support the hope in this research and click HERE


Patient Assistance Programs are offered by many pharmaceutical manufacturers to help pay for medications. These offers are sometimes called Indigent Drug Programs. Use our link just following, and learn whether a specific drug might be available at reduced cost or for free.

Drug Assistance Programs: click HERE

At the Mesothelioma Research Foundation of America, you can call toll free (800) 909-Meso (6376) to talk with one of our Cancer Information Specialists who will gladly look up the phone numbers or the web site of the pharmaceutical company that makes the drug you are using


Find the lastest Mesothelioma clinical trials: click HERE

To ask your Cancer questions: click HERE

Help this Foundation and click HERE


Cancer imposes heavy economic burdens on a cancer patients and family members alike. Resources are available for individuals who do not have health insurance or who need financial assistance to cover health care costs. Our listing will help you find Government agencies, private organizations, and programs that are designed to provide assistance for a cancer patient and their family.

Financial help for cancer patients: click HERE

At the Mesothelioma Research Foundation of America, you can call toll free (800) 909-Meso (6376) to talk with one of our Cancer Information Specialists who will gladly look up the phone numbers or the web site of organizations that provide financial assistance.

Bring us your Mesothelioma cancer questions: click HERE

Help grow the Foundation and cancer-cure research: click HERE

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Press Release: April 9, 2015

GRAPHENE – New Research That May Help Mesothelioma Victims

An international team of researchers has developed a drug delivery technique that utilizes Graphene strips as “flying carpets” to deliver two anticancer drugs sequentially to cancer cells, with each drug targeting the distinct part of the cell where it will be most effective. The technique was found to perform better than either drug in isolation when tested in a mouse model targeting a human lung cancer tumor.

GRAPHENE has successfully proved itself in the lab against six kinds of cancer cells. Flaked Graphene oxide preferentially hits these cancers right in the stem cells. These are the guys that not only are often responsible for starting the tumor, but they also tend to stick around after the radiation, chemotherapy, and surgery to reseed a tumor just when it looks like it was defeated.

Jerry Neil Paul, a Founding Board Member of the Mesothelioma Research Foundation of America, has an objective to bring encouragement to cancer patients who are victims of mesothelioma. This recent cancer cure research from North Carolina State University , and the University of North Carolina at Chapel Hill, as well as the China Pharmaceutical University have also found a protein, TRAIL, that is anti-cancerous. This protein can be used to serve as an active targeting molecule that binds directly to a cancer cell.

Current research studies using Graphene strips show that anti-cancer drugs can be attached to the Graphene for focused delivery to the cancer cell. Graphene is particularly useful for this because it is a two-dimensional sheet of carbon only one atom in thickness. While the Mesothelioma Research Foundation of America has developed Veglin and EphB4, and others have developed TRAIL and Doxorubiein (Dox), non-chemotherapy drug treatments, all the treatments could be conducive to a Graphene strip delivery method. The Graphene delivery method is useful when the oncologist wants an effective sequential application of two drugs that work together, where each drug kills the cancer cell where it will be most effective. Some drug treat ments attach to the external membrane of the cancer cell to kill it, while other drug treatments effectively kill the cancer cell when delivered to the cell nucleus.

The Graphene strip works when a cancer drug treatment can be physically integrated and bound to it because of similar molecular structures of Graphene and the drug. So, various drug treatments can be attached to the surface of the Graphene by a combination of amino acids known as peptides.

Dr. Parkish Gill, on behalf of the Mesothelioma Research Foundation of America will determine if there is a way to apply and proceed with his non-chemotherapy treatments using the Graphene strip technique.

The paper, “Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene,” was published in early view online Dec. 15 in Advanced Materials. Lead author of the paper is Dr. Tianyue Jiang, a former graduate student lab-researcher on the study who is now on faculty at Nanjing Tech University . The co-corresponding author is Dr. Ran Mo, who is also a former postdoctoral lab-researcher on this project who is now on faculty at CPU. Co-authors include Wujin Sun, a Ph.D. student in the lab of this project; Qiuwen Zhu, a Ph.D. student at CPU; Nancy Burns, a Ph.D. student at NC State; and Dr. Saad Khan, Alcoa Professor of Chemical and Biomolecular Engineering at NC State.


THE FOUNDATION

The Mesothelioma Research Foundation of America has a mission: fund research that will lead to the quickest cure for mesothelioma. Mesothelioma is a cancer of the lining of the lungs caused by asbestos exposure. This cancer disease had few treatment options until this Foundation and Dr. Parkash Gill's work created better treatment options. Today, the future looks more hopeful for additional improved treatment options available to those stricken by this cancer.

James W. Kellogg, Jerry Neil Paul, Elizabeth Paul and Dr. Parkash Gill, M.D.
The Foundation Board Members from the left are: James W. Kellogg, Jerry Neil Paul, Elizabeth Ann Paul and Dr. Parkash Gill, M.D. These are respectively the United Association International Representative, Founding Director, Executive Director and Chairman of the Medical Advisory Board.

 

The Mesothelioma Research Foundation of America began funding research for a cure in 2001 with the opening of the Mesothelioma Laboratory at USC Norris Comprehensive Cancer Medical Center in Los Angeles under the supervision of Dr. Parkash Gill.

Dr. Gill is a board certified oncologist and hematologist who has received FDA approval from the U.S. Government to do Clinical Trials on a mesothelioma treatment drug called Veglin. We believe there is great promise and hope in Veglin and the Mesothelioma Research Foundation of America has funded 100% of Dr. Gill's research.

Veglin proved successful in Phase I and Phase II clinical trials. Many are very hopeful for the possibilities of a more effective cancer treatment compared to what presently is available for mesothelioma victims. We are currently in FDA approved Clinical Trials with EPH-B4 which replaced the Veglin Trials.


DISTRICT COUNCIL 16 GIVES $200,000
FOR CANCER RESEARCH

Money Goes to Effective, Ongoing Research and Treatment

By Robert Buscemi

The United Association Southern California Pipe Trades Council 16 presented the Mesothelioma Research Foundation of America with a check for $200,000 at the Council's annual holiday lunch.

MesoRFA and District Council 16
DC 16 gives a landmark amount to a worthy cause: (l-r) Shane Rucker, Dr. Parkash Gill, Elizabeth Paul, Jerry Neil Paul and John Ferruccio.

The money, all raised in 2014, will go toward a cure for mesothelioma, a cancer caused by exposure to asbestos. District Council 16 Director of Organizing John Ferruccio emceed the event December 12 at the Dodger Stadium Club. He held off announcing the impressive dollar figure until after the speeches, when a drum roll from the house band built the excitement.

“Every year, as you know, one of our main fundraisers is to find a cure for this unfortunate disease,” Ferruccio told more than 150 attendees. “Mostly, mesothelioma is affecting our grandfathers, fathers and fathers-in-law. It's gotten a lot better over the years.”

Ferruccio said the Council hosts an annual golf tournament and skeet-shooting events. In addition, the State Building and Construction Trade Council of California raises money through the annual Roger Hamilton golf invitational.

The foundation, known as MESORFA, was founded in 2001 by attorney Jerry Neil Paul, his wife Elizabeth Ann Paul and retired California Pipe Trades Representative and past Vice President of the State Building and Construction Trade Council, Jim Kellogg.

MesoRFA and Elizabeth Paul
"To bring a treatment to the public costs tens of millions of dollars," Elizabeth Paul tells the crowd.

In thanking District Council 16, MESORFA Executive Director Elizabeth Paul explained that all funding goes toward research rather than administration. “All of this money goes directly to fund a lab at USC Norris Comprehensive Cancer Center here in Los Angeles . We use 100 percent of every dollar donated toward research, for clinical trials and to fund the lab. Nothing goes for the foundation – those costs are privately underwritten.”

Research Costs Millions

Paul said such research is never cheap, and other cancers get more attention and funding than mesothelioma, especially in a tight economy. Indeed, she said, MESORFA operates on a shoestring budget. “I know people don't understand that, but to bring a treatment to the public costs tens of millions of dollars.”

As such, Paul said District Council 16's annual contribution is crucial. “Everybody was extremely generous. Families took care of families. My husband Jerry and I are big on family. Your leaders at District Council 16 view your members as family. Because they have gone out of their way to make sure that there are treatments and cures for this horrible disease.”

The disease hits especially hard at workers who have been exposed to asbestos, as many Pipe Trades and other Building Trades were before protections were put in place against the toxic substance. Even now, workers confront the hazard at some job sites.

Paul then introduced Dr. Parkash Gill, who reported that he has made huge strides at his lab through the development of Veglin, a drug that treats the disease. “I'm honored to be part of it,” Gill said. “It's a worthy cause. I'm a cancer doctor, so finding a treatment for patients really is a rewarding experience. When somebody is ill and they get better and they go home and never see you again, it's wonderful.”

Gill said that patients are already seeing positive results at treatment advances. He said certain efforts have been completely successful. “This medicine, we have given to a 78-year-old patient. Two or three years out now, there's no cancer left and no side effects.”


Clinical Trials Status

Dr. Parkish Gill seeks  cure for mesothelioma cancer
Dr. Parkash Gill

 

Dr. Parkash Gill of the USC Norris Comprehensive Cancer Center has announced that the new cancer fighting drug EPH-B4 has been submitted to the FDA for Phase I Clinical Trials and is available to qualifying mesothelioma patients. In the initial Phase I Trial EPH-B4 is available to newly diagnosed patients who have not undergone any conventional treatment options and to those patients who have exhausted all other treatment options such as surgery and chemotherapy. This is truly exciting as Dr. Gill has reported that EPH-B4 has shown great promise as a solo treatment or in conjunction with other drugs as Alimta, Cisplatin and Carboplatin.


Please use our FaceBook link to obtain your FREE copy of our eBook that teaches:

10 Easy Steps On How To Find And Choose A Clinical Trial For Mesothelioma And How To Prepare For It!

Ask us questions about your specific mesothelioma issues here: Ask Questions

In addition to the eBook found at our Facebook fan page, also learn more about clinical trials from these links:


February 15, 2014

There have been significant improvements creating new options for patients with Mesothelioma lung cancer. This video presents the new options for a patient to be aware of and consider. This news release video, created by Med Page Today, is about Oncology and Lung Cancer has been shared on YouTube by the Mesothelioma Research Foundation of America.

 

 


Lyons Foundation Chooses MesoRFA

The Mesothelioma Research Foundation of America is the proud recipient of a grant from the John S. Lyons Memorial Foundation, charitable branch of the San Diego Building Trades Councel, to help support clinical studies of Dr. Parkash Gill's protein known as EPH B4 as a mesothelioma cancer treatment option.

John S. Lyons Memorial Foundation

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